Mpox Remains a Global Concern as Clade Ib Continues to Spread

Mpox has not disappeared. CDC reports that the global clade IIb outbreak that began in 2022 has caused more than 100,000 cases across 122 countries. At the same time, WHO continues to track clade Ib mpox, including recent first detections in countries such as Colombia, Denmark, Ecuador, and Singapore.

Mpox usually spreads through close physical contact, including intimate contact, and can cause fever, swollen lymph nodes, fatigue, and painful rash or lesions. CDC recommends two doses of JYNNEOS vaccine, given 4 weeks apart, for people at increased risk; data from several studies show stronger protection after two doses than one.

Yes2Vaccines message: Mpox control depends on surveillance, stigma-free education, early testing, isolation when sick, and vaccination for people at higher risk.